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Lilian Weng Leaves Thinking Machines Citing Health, Rejoins OpenAI Days Later

Thinking Machines Lab co-founder Lilian Weng announced her departure from the AI startup this week, citing the physical toll of startup-level stress, only to resurface at OpenAI within 48 hours to lead one of the company's most closely watched research programs.

Key Takeaways

  • Weng told colleagues in an internal Slack message, later shared on X, that she could no longer sustain the pace a startup requires after months of consistent stress and workload.
  • OpenAI confirmed Wednesday that Weng is returning to lead a top-level team focused on recursive self-improvement, the process of using AI to make AI systems more capable.
  • Thinking Machines co-founder Mira Murati publicly supported Weng’s decision on X, though it remains unclear whether Murati knew Weng would land back at OpenAI.
  • Weng becomes the fourth co-founder to leave Thinking Machines since Murati launched the company in February 2025, with 13 of its 42 founding members departing by May.

Thinking Machines co-founder Lilian Weng’s exit note, shared on X, read as unusually candid for a founder departure in the AI industry.

She wrote that she had tried resting while the lab raced to ship its first open-weight model, Inkling, but felt persistent guilt, and had considered a narrower role before deciding that staying on in a reduced capacity wasn’t who she was.

Fellow co-founder Mira Murati replied that she’d miss Weng and was glad she was putting her health first, thanking her for helping build the company. However, OpenAI later told TechCrunch that Weng will rejoin the company. 

From Exit Note to New Job in Two Days

The outlet reported that Weng announced her departure on Tuesday and was confirmed as returning to ChatGPT creator OpenAI by Wednesday, prompting questions about her need to step back from startup intensity to taking another high-profile research role. 

TechCrunch noted the tension, saying the move could appear to contradict her stated reasons for leaving, though she likely won’t face the same pressure at a company where she isn’t a co-founder responsible for its trajectory. 

Weng previously spent nearly seven years at OpenAI, from 2018 to 2024, building its safety infrastructure, including its fine-tuning API and moderation systems, before leaving to co-found Thinking Machines with Murati in early 2025.

A Pattern of Health-Driven Exits Among AI’s Second Tier

Business Insider’s reporting placed Weng’s departure within a broader pattern emerging across AI labs this year, noting that her exit note described being ill more often over the past seven months than at any point in her life, and that she did not name a specific diagnosis. 

The report drew a direct comparison to OpenAI’s own Fidji Simo, who stepped back from a top role this month following a flare-up of a chronic illness, and Greg Yang, the cofounder of SpaceX’s merged subsidiary xAI, who moved into an advisory position in January after a Lyme disease diagnosis. 

Business Insider observed that the executives stepping away under these circumstances have tended to sit one level below the very top of their organizations, even as some Silicon Valley AI teams continue running punishing six-day weekly schedules that show no sign of slowing regardless of who burns out along the way.

A Thinning Founding Team at Thinking Machines

Weng’s return to OpenAI also underscores just how much turnover Thinking Machines has absorbed since its high-profile launch. 

TechCrunch’s coverage noted that Weng represents a significant, high-profile departure amid what is already fierce competition for AI talent.

Business Insider added that her exit continues a steady thinning of the startup’s original team, with only two of the six founding co-founders now remaining at the company. 

That erosion comes despite Thinking Machines raising a $2 billion seed round led by Andreessen Horowitz, underscoring that even well-funded, high-profile AI startups aren’t immune to the pull of established labs like OpenAI. 

Source: Lilian Weng left the company citing health reasons, then joined OpenAI

Fawad Malik

Fawad Malik is a digital marketing professional and technology writer with over 15 years of industry experience. He specializes in SEO, SaaS, AI, consumer technology, internet services, and content strategy. He is the Founder and CEO of WebTech Solutions, a digital agency focused on helping businesses grow through modern online strategies. Through NogenTech, Fawad shares practical insights on internet technology, WiFi, apps, AI tools, digital trends, and the latest tech updates for readers worldwide.

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